Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants
… Our key defense against the COVID-19 pandemic is neutralizing antibodies
… Recent emerging viral variants have raised concern
… to escape antibody neutralization
… four antibodies from early-outbreak convalescent donors
… potent against 23 variants, including variants of concern
… Our study demonstrates that convalescent subjects previously infected with ancestral variant SARS-CoV-2 produce antibodies that cross-neutralize emerging VOCs with high potency