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Rates of COVID-19 among UNVACCINATED adults with PRIOR COVID-19

20 Aprile 2022 by

… We performed a survival analysis in a large US population

… at 1300 sites of care in 6 western US states

… between October 1, 2020, and November 21, 2021

… patients with prior COVID-19 (positive for SARS-CoV-2 on their initial test [cases])

… patients who tested negative for SARS-CoV-2 on their initial test (controls)

… identified 24043 cases and 97 572 controls

… 2762 controls (2.8%) developed COVID-19

… compared with 98 cases (0.4%)

… Among 121 615 patients with more than 10 million days of follow-up

… unvaccinated individuals with prior symptomatic COVID-19 had 85% lower risk of acquiring COVID-19

… This level of protection is similar to that reported for mRNA vaccines

… 88% protection against hospitalization

… 83% protection against COVID-19 not requiring hospitalization

… Strengths include large sample size, long duration of follow-up, and inclusion of only unvaccinated individuals with symptomatic COVID-19